Call for Case Reports – Pediatric Acute Hepatitis of Unknown Etiology

From the NDDoH:

HEALTH ALERT NETWORK | HEALTH ADVISORY | April 22, 2022

Call for Case Reports – Pediatric Acute Hepatitis of Unknown Etiology The North Dakota Department of Health is providing this information regarding multiple reports of acute hepatitis of unknown etiology in children from the United States and United Kingdom.

When evaluating patients with acute hepatitis providers are encouraged to add testing for adenovirus infections if other etiologies (i.e., hepatitis A, B, C, D or E) have been ruled out. CDC is requesting notification from clinicians on children <10 years of age with elevated aspartate aminotransferase (AST) or alanine aminotransferase (ALT) (>500 U/L) who have an unknown etiology for their hepatitis (with or without any adenovirus testing results, independent of the results) since October 1, 2021.

If you are currently caring for patients or have residual specimens, please save and freeze them for possible additional testing. Any patient meeting these criteria should be reported to the North Dakota Department of Health by calling 701-328-2378 or 1-800-472-2180. Reports made to the North Dakota Department of Health will be forwarded to the CDC. Assistance with laboratory testing can be obtained by calling the Laboratory
Services Section at 701-328-6272.